Treatment options

The current practice of treating allergies relies mostly on avoiding the allergen altogether or using medication to relieve the symptoms.

Avoidance is feasible with animal or food allergies, but can severely limit certain activities and social aspects of life. With pollen allergies it is even more difficult to avoid the allergen as pollen travels long distances with the winds.

The most common medicinal remedies are antihistamines, decongestants, corticosteroids and bronchodilators. Some of them are over-the-counter products, some require a prescription. Antihistamines and decongestants counteract the effect of histamine by blocking the histamine receptors or by inducing local vasoconstriction, respectively. Corticosteroids control inflammation and bronchodilators ease breathing in asthma by dilating the respiratory airways. All of these drugs are designed to alleviate specific symptoms. They don't affect the underlying allergic condition.

Allergen immunotherapy is a method where gradually increasing doses of the allergen are administered. This desensitizes the body and tweaks the immune response away from the allergic mechanism, towards a healthy response. Immunotherapy reduces or eliminates allergic symptoms caused by the specific allergen, and the effect remains even after the treatment period is over. However, traditional allergen immunotherapy with natural allergens takes a long time, and requires careful medical supervision to minimize the risk of a serious allergic reaction (anaphylaxis).

Desentum develops immunotherapeutic hypoallergens that offer the long-lasting effect of specific immunotherapy without the long treatment period and risk of anaphylaxis. Read more about our products.